microRNA Microarray Analysis Service
As a leading service provider in the field of microarrays, CD Genomics is committed to the design and development of various effective biological microarrays for scientific research and non-clinical research. Our microarray test platform provides a full range of microarray-based microRNA analysis and testing services to help our global customers conduct relevant research and reduce research costs. With our time-tested capabilities and regulatory expertise, we are confident to provide quality services in related testing services to escort your research.
Microarray and MicroRNA Expression Profiling
MicroRNA (miRNA) is a short non-coding RNA molecule that plays a role in the post-transcriptional regulation of gene expression. miRNA can be used as a guide molecule to initiate protein translation inhibition by partially or completely binding to the target mRNA in the 3'untranslated region. More and more studies have shown that miRNA is involved in a variety of cellular pathways, including cell proliferation, differentiation, and apoptosis. Therefore, the study of miRNA expression profiles is becoming more and more important. miRNA and transcript are interdependent and usually form a feedback loop. One disorder may alter the expression of the other, and both are involved in many physiological processes, including immune regulation. Bioinformatics and genetic analysis indicate that the miRNA genes present in the genomes of mice, humans, fruit flies, Caenorhabditis elegans, Arabidopsis, viruses, and fungi are unique and are expressed in a controlled manner. Many miRNAs are highly conserved in animals and plants and have unique tissue-specific, developmental stage-specific, or disease-specific patterns. Microarrays have made important contributions to related basic research and applied research, and transformed the medical practice into more personalized research.
Fig 1. Flow chart for a miRNA array platform. (Yin J Q, et al. 2008)
Service Process
Our microarray miRNA expression analysis service is designed to study the role of miRNA in biogenesis, tissue distribution, the difference between normal and abnormal miRNA expression, disease characteristics, stem cell development, pathway mapping, mechanism of action, and tumorigenesis Scientific research workers provide assistance. The probe content comes from the National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database and our own database. You can choose to customize microarray products with different specifications and probe numbers for testing. The specific service process includes customized service content, microarray design, printing, testing, data analysis, and annotation.
- Customize Service Content. The content of the service selected according to scientific research needs is customized microarray products or/and follow-up testing services.
- Microarray Design, Printing, and Testing. Design microarray probes according to scientific research needs. Our expression analysis service can accept biological samples (cells, blood, tissues, miRNA nucleic acid samples) from humans and model organisms. The industry-leading microarray machine is used to provide ready-made consumables for customized microarray printing. In addition, we also include a microarray testing experimental platform, which can provide further testing services.
- Data Analysis and Annotation. Our bioinformatics team provides follow-up data analysis and annotation services.
Fig 2. CD Genomics's miRNA detection process.
Our Features and Benefits
- High-throughput Detection. The advantage of the microarray experimental platform is to study gene expression patterns by measuring the expression levels of hundreds to thousands of target molecules at a time.
- One-stop Service. Our strong bioinformatics team provides data analysis and annotation.
- Supporting Services. Industry-leading equipment and technology can help you conduct scientific research.
CD Genomics provides miRNA detection services based on convenient microarrays. We have a large and well-equipped team of scientists who are committed to cooperating with researchers from all over the world to meet customer requirements. Customers can directly contact our employees and provide timely feedback on their inquiries. If you are interested in our one-stop solution service, please contact us for more detailed information.
References
- Yin J Q, Zhao R C, Morris K V. Profiling microRNA expression with microarrays[J]. Trends in biotechnology, 2008, 26(2): 70-76.
- Liu C G, Calin G A, Volinia S, et al. MicroRNA expression profiling using microarrays[J]. Nature protocols, 2008, 3(4): 563.
Our products and services are for research purposes ONLY. We do not perform any private testing services that are not for laboratory use.
